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Provide your input to the implementation and revision process of the JPIAMR Strategic Research Agenda for the Environmental Dimensions of AMR

 

The Joint Programming Initiative for Antimicrobial Resistance (JPIAMR) is in the process of updating its strategic research agenda (SRA). On behalf of the JPIAMR, together with the Swedish Research Council VR, we are arranging a small workshop with ca 20 invited experts to provide input to the implementation and revision process of the SRA with regards to the Environmental Dimensions of AMR. The purpose of the workshop is to explore and identify critical research needs.

To capture research needs more efficiently we urge anyone with interest in the subject to provide input in terms of what knowledge gaps they think should receive priority. Please provide your input to the revised SRA using the form below. Deadline for submission is September 17th.

 

Submit your input here.

 

The JPIAMR brings together 23 Member countries, which aim to pool national research efforts to tackle AMR, and to better align national and international strategies. The workshop will be held in Gothenburg, Sweden 27-28th of September, and be led by Professor Joakim Larsson. The participants will divide into three breakout groups focusing on the three thematic aspects indicated below, and report back their work to the whole group. The group will identify both long and short-term research needs. Results will be published as a JPIAMR report.

Theme 1. Evolution and selection in the environment

The environment hosts a vast diversity of bacteria and bacterial genes, and is believed to act as a source for resistance factors to pathogens. Selection pressures outside of the bodies of humans and animals may facilitate in this process. This may include direct selection pressures from antibiotics but also indirect selection via e.g. certain metals and antibacterial biocides. Understanding the environment´s involvement in the evolution and emergence of resistance in pathogens would fall under this theme, as well as the role human activities have on such processes. Understanding the relation between exposure level to selective agents and the development of resistance in different setting is one of the questions to address.

Rapporteur: Joakim Larsson

Theme 2. Transmission of resistant bacteria via the environment

Many pathogens, including antibiotic resistant bacteria, spread via contaminated water and soils and may eventually lead to increased infection of humans and animals. Understanding the role of different environments, conditions and practices in the transmission of bacteria in the environment, particularly resistant bacteria, from the source all the way to humans/animals would fall under this theme. This also includes approaches to quantify risks.

Rapporteur: Ana-Maria de Roda Husman

Theme 3. Interventions related to the external environment

Interventions to reduce the spread of resistant bacteria and selective agents to environment and to prevent infection from environmental sources can be both technical and of a more social nature, i.e. measures to incentive change. The possibilities and need for interventions will differ not only between sectors (human, animal and industrial sources) but also between regions (low, middle and high-income countries) with radically different infrastructure for waste management. Identifying research gaps that address critical needs in all these sectors and regions will be within scope of this theme.

Rapporteur: Ramanan Laxminarayan

 

It is acknowledged that there is some overlap between the three themes; i.e. selection may influence not only evolution but also transmission; investigating different levels of transmission under different practices has clear links to practical interventions, and so on. However, we feel this is unavoidable. Also, the environment priority topic has an overlap to several of the other priority topics of the SRA, not the least on the intervention side. Here, only interventions, aspects on selection and transmission that occur outside of the human/animal body will be covered.

 

 

Page Manager: Webbredaktionen|Last update: 8/21/2017
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