Videos in this resource go through the basics of the science behind the antibiotic crisis.
[9 May 2018] The Swedish Government decided today to support installation of advanced sewage treatment in order to more efficiently remove pharmaceutical residues and reduce risks for antibiotic resistance development
[7 May 2018] This review provides guidance to what knowledge gaps are critical to fill, in order to better manage risks related to antibiotic resistance from environmental sources.
[7 May 2018] Sialic acid transporters are required for sialic acid uptake in a number of human pathogens and are of interest as targets for antimicrobial drug development. Researchers from CARe have now functionally characterised and determined the substrate bound structure of the sialic acid transporter from the uropathogen Proteus mirabilis. The study provide insights into the mechanism of sialic acid transport and is a stepping stone for structure based drug-design. The study was published in Nature Communications.
[26 Apr 2018] Ciprofloaxin is a potent and relatively stable synthetic antibiotic. Hence, there may be risks for selection for resistance when it is released into the environment. In a study published this week in the journal Environment International, CARe researchers studied what concentrations were required to select for resistance (as measured by several endpoints) in complex aquatic biofilms. The results may be used for guiding regulation as well other voluntary initiatives to reduce risks associated with environmental antibiotic pollution.
[24 Apr 2018] In this study, CARe researchers have compared different methods for correction ('normalization') of data from shotgun metagenomics.
[19 Apr 2018] The article assess ethical aspects of using person-centered care consultations (PCC), where clinicians may openly criticise or contradict patient beliefs, perceptions, preferences or values, in order to influence patient behavior in various directs, such as acceptance of and conformity to antibiotic stewardship programs with restricted prescription practices. The authors argue that, while such use of PCC may bring specific ethical aspects ti mind about and be quite problematic in some areas, using for public health purposes of this sort csn be ethically acceptable. Munthe C, El-Alti L, Hartvigsson T, Nijsingh N 2018. Journal of Argumentation in Context, Accepted and in press.
[18 Apr 2018] This course is open to everyone interested in antibiotic resistance, however a bachelor of science is recommended.
"This serious threat is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country"
"Without urgent, coordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and minor injuries which have been treatable for decades can once again kill"
(World Health Organization 2014 regarding the global challenges with antibiotic resistance)
“It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them… There is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.”
(Alexander Flemming, Nobel Lecture, December 11, 1945)
"Ethics and Value Challenges in Antibiotic Resistance Management, Policy and Research Symposium"
See all talks from the first ever major international conference on this topic.
External links to more information about antibiotic resistance (Photo:NIAID)
