Publications

Peer-reviewed publications by CARe

2023

2022

Tell D, Tyrstrup M, Edlund C, Rystedt K, Skoog Ståhlgren G, Sundvall PD, Hedin K. (2022). Clinical course of pharyngotonsillitis with group A streptococcus treated with different penicillin V strategies, divided in groups of Centor Score 3 and 4: a prospective study in primary care. BMC Infect Dis. 22:840. https://doi.org/10.1186/s12879-022-07830-4
Hartman EAR, Groen WG, Heltveit-Olsen SR, Lindbæk M, Høye S, Sundvall PD, Skoglund I, Snaebjörnsson Arnljots E, Gunnarsson R, Kowalczyk A, Godycki-Cwirko M, Kosiek K, Platteel TN, van de Pol AC, Verheij TJM, Monnier AA, Hertogh CMPM. (2022). Decisions on antibiotic prescribing for suspected urinary tract infections in frail older adults: a qualitative study in four European countries. Age and Ageing. 51(6):afac134. https://doi.org/10.1093/ageing/afac134
Marathe NP, Salvà-Serra F, Nimje PS, Moore ERB. (2022). Novel plasmid carrying mobile colistin resistance gene mcr-4.3 and mercury resistance genes in Shewanella baltica: insights into mobilization of mcr-4.3 in Shewanella species. Microbiology Spectrum. e02037-22. https://doi.org/10.1128/spectrum.02037-22
Salvà-Serra F, Jaén-Luchoro D, Marathe NP, Adlerberth I, Moore ERB, Karlsson R. (2022). Responses of carbapenemase-producing and non-producing carbapenem-resistant Pseudomonas aeruginosa strains to meropenem revealed by quantitative tandem mass spectrometry proteomics. Preprint from bioRxiv. https://doi.org/10.1101/2022.10.23.513223
Trobos M, Firdaus R, Svensson Malchau K, Tillander J, Arnellos D, Rolfson O, Thomsen P, Lasa I. (2022). Genomics of Staphylococcus aureus and Staphylococcus epidermidis from periprosthetic joint infections and correlation to clinical outcome. Microbiol Spectr. 10(4):e0218121. https://doi.org/10.1128/spectrum.02181-21
Morales-Laverde L, Echeverz M, Trobos M, Solano C, Lasa I. (2022). Experimental polymorphism survey in intergenic regions of the icaADBCR locus in Staphylococcus aureus isolates from periprosthetic joint infections. Microorganisms. 10(3):600. https://doi.org/10.3390/microorganisms10030600
Munthe C, Malmqvist E, Rönnerstrand B. (2022). Non-prescription acquisition of antibiotics: Prevalence, motives, pathways and explanatory factors in the Swedish population. PLoS ONE 17(9): e0273117. https://doi.org/10.1371/journal.pone.0273117
Jaén-Luchoro D, Al-Shaer S, Piñeiro-Iglesias B, Gonzales-Siles L, Cardew S, Jensie-Markopolous S, Ohlén M, Inganäs E, Neumann-Schaal M, Wolf J, Moore ERB. (2022). Corynebacterium genitalium sp. nov., nom. rev. and Corynebacterium pseudogenitalium sp. nov., nom. rev., two old species of the genus Corynebacterium described from clinical and environmental samples. Research in Microbiology. 103987. https://doi.org/10.1016/j.resmic.2022.103987
Papadimou D, Malmqvist E, Ancillotti M. (2022). Socio-cultural determinants of antibiotic resistance: a qualitative study of Greeks’ attitudes, perceptions and values. BMC Publ Health. 22:1439. https://doi.org/10.1186/s12889-022-13855-w
Van Wonterghem L, De Chiara M, Liti G, Warringer J, Farewell A, Verstraeten N, Michiels J. (2022). Genome-wide association study reveals host factors affecting conjugation in Escherichia coli. Microorganisms. 10(3):608. https://doi.org/10.3390/microorganisms10030608
Lindblom A, Kiszakiewicz C, Kristiansson E, Yazdanshenas S, Kamenska N, Karami N, Åhrén C. (2022). The impact of the ST131 clone on recurrent ESBL-producing E. coli urinary tract infection: a prospective comparative study. Sci Rep. 12:10048. https://doi.org/10.1038/s41598-022-14177-y
Larsson DGJ, Flach C-F, Laxminarayan R. (2022). Sewage surveillance of antibiotic resistance holds both opportunities and challenges. Nature Reviews Microbiology. https://doi.org/10.1038/s41579-022-00835-5
Munk P, Brinch C, Møller F, Petersen T, Hendriksen R, Seyfarth A, Kjeldgaard J, Svendsen C, van Bunnik B, Berglund F, Global Sewage Surveillance Consortium, Larsson DGJ, Koopmans M, Woolhouse M, Aarestrup F. (2022). Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance. Nature Communications. 13:7251. https://doi.org/10.1038/s41467-022-34312-7
Guzman-Otazo J, Joffré E, Agramont J, Mamani N, Jutkina J, Boulund F, Hu YOO, Jumilla-Lorenz D, Farewell A, Larsson DGJ, Flach C-F, Iñiguez Rojas V, Sjöling Å. (2022). Conjugative transfer of multi-drug resistance IncN plasmids from environmental waterborne bacteria to Escherichia coli. Frontiers in Microbiology. 13:997849. https://doi.org/10.3389/fmicb.2022.997849
Palm M, Fransson A, Hultén J, Búcaro Stenman K, Allouche A, Chiang OE, Constandse ML, van Dijk KJ, Icli S, Klimesova B, Korhonen E, Martínez-Crespo G, Meggers D, Naydenova M, Polychronopoulou MA, Schuntermann DB, Unal H, Wasylkowska A, Farewell A. (2022). The effect of heavy metals on conjugation efficiency of an F-plasmid in Escherichia coli. Antibiotics. 11:1123. https://doi.org/10.3390/antibiotics11081123
Bourgard C, Hernández DR, Rudenko A, Rutgersson C, Palm M, Larsson DGJ, Farewell A, Grøtli M, Sunnerhagen P. (2022). Development of dicationic bisguanidine-arylfuran derivatives as potent agents against Gram-negative bacteria. Antibiotics. 11:1115. https://doi.org/10.3390/antibiotics11081115
RiquelmeMVP, Garner E, Gupta S, Metch J, Zhu N,BlairMF, Arango-ArgotyG, Maile-MoskowitzA, LiA-D, Flach C-F, AgaDS, NambiIM, LarssonDGJ, BürgmannH, ZhangT, Pruden A, Vikesland PJ. (2022). Demonstrating a comprehensive wastewater based surveillance approach that differentiates globally sourced resistomes. Environmental Science and Technology. 56(21):14982–14993. https://doi.org/10.1021/acs.est.1c08673
Larsson DGJ, Flach C-F. (2022). Antibiotic resistance in the environment. Nature Reviews Microbiology. 20:257. https://doi.org/10.1038/s41579-021-00649-x
Rönnerstrand B, Carelli D, Pierre J, Lampi E. (2022). Leviathan versus the super bugs: free riding drives support for EU power over antimicrobial resistance. Journal of European Integration, 44(8):1041-1057. https://doi.org/10.1080/07036337.2022.2068539
Han Z, Feng H, Luan X, Shen Y, Deng L, Larsson DGJ, Gillings M, Zhang Y, Yang M. (2022). Three-year consecutive field application of erythromycin fermentation residue following hydrothermal treatment: Cumulative effect on soil antibiotic resistance genes. Engineering. 15:78-88. https://doi.org/10.1016/j.eng.2022.05.011
Rodríguez-Molina D, Berglund F, Blaak H, Flach C-F, Kemper M, Marutescu L, Gradisteanu LP, Popa M, Spießberger B, Wengenroth L, Chifiriuc MC, Larsson DGJ, Nowak D, Radon K, de Roda Husman AM, Wieser A, Schmitt H. (2022). International travel as a risk factor for carriage of extended-spectrum β-lactamase-producing Escherichia coli in a large sample of European individuals - The AWARE Study. International Journal of Environmental Research and Public Health. 19(8):4758. https://doi.org/10.3390/ijerph19084758
Ebmeyer S, Coertze RD, Berglund F, Kristiansson K, Larsson DGJ. (2022). GEnView: a gene-centric, phylogeny-based comparative genomics pipeline for bacterial genomes and plasmids. Bioinformatics. 38, 6:1727. https://doi.org/10.1093/bioinformatics/btab855
Hutinel M, Larsson DGJ, Flach C-F. (2022). Antibiotic resistance genes of emerging concern in municipal and hospital wastewater from a major Swedish city. Science of the Total Environment. 812 https://doi.org/10.1016/j.scitotenv.2021.151433

2021

Kondori N, Kurtovic A, Piñeiro-Iglesias B, Salvà-Serra F, Jaén-Luchoro D, Andersson B, Alves G, Ogurtsov A, Thorsell A, Fuchs J, Tunovic T, Kamenska N, Karlsson A, Yu Y-K, Moore ERB, Karlsson R. (2021). Mass spectrometry proteotyping-based detection and identification of Staphylococcus aureus, Escherichia coli, and Candida albicans in blood. Front. Cell. Infect. Microbiol. 11:634215. https://doi.org/10.3389/fcimb.2021.634215
Kieffer N, Ebmeyer S, Larsson DGJ. (2021). Evidence for Pseudoxanthomonas mexicana as the recent origin of the blaAIM-1 carbapenemase gene. International Journal of Antimicrobial Agents. 59(4): 106571. https://doi.org/10.1016/j.ijantimicag.2022.106571
Lund D, Kieffer N, Parras-Moltó M, Ebmeyer S, Berglund F, Johnning A, Larsson DGJ, Kristiansson E. (2021). Large-scale characterization of the macrolide resistome reveals high diversity and several new pathogen-associated genes. Microbial Genomics. 8(1):000770. https://doi.org/10.1099/mgen.0.000770
Dai D, Brown C, Bürgmann HD, Larsson DGJ, Nambi I, Zhang T, Flach C-F, Pruden A, Vikesland PJ. (2021). Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge. Microbiome. 10(20). https://doi.org/10.1186/s40168-021-01216-5
Malmqvist E, Fumagalli D, Munthe C, Larsson DGJ. (2021). Pharmaceutical pollution from human use and the Polluter Pays Principle. Submitted. Preprint. https://doi.org/10.13140/RG.2.2.34475.98088/1
Gerner E, Almqvist S, Thomsen P, Werthen M, Trobos M. (2021). Sodium salicylate influences the Pseudomonas aeruginosa biofilm structure and susceptibility towards silver. International journal of molecular sciences. 22(3):1060. https://doi.org/10.3390/ijms22031060
Djerf-Pierre M, Lindgren M. (2021). Making sense of “superbugs” on YouTube: A storytelling approach. Public Understanding of Science. https://doi.org/10.1177/0963662521989251
EFSA Panel on Biological Hazards (BIOHAZ), Allende A, Koutsoumanis K, Alvarez-Ordóñez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Herman L, Hilbert F, Lindqvist R, Nauta M, Ru G, Simmons M, Skandamis P, Suffredini E, Andersson DI, Bampidis V, Bengtsson-Palme J, Bouchard D, Ferran A, Kouba M, López Puente S, López-Alonso M, Saxmose Nielsen S, Pechová A, Petkova M, Girault S, Broglia A, Guerra B, Lorenzo Innocenti M, Liébana E, López-Gálvez G, Manini P, Stella P, Peixe L (2021). Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. EFSA Journal. 19(10): e06852. https://doi.org/10.2903/j.efsa.2021.6852
Atefyekta S, Blomstrand E, Rajasekharan AK, Svensson S, Trobos M, Hong J, Webster TJ, Thomsen P, Andersson M. (2021). Antimicrobial peptide-functionalized mesoporous hydrogels. ACS Biomaterials Science & Engineering. 7(4):1693–1702. https://doi.org/10.1021/acsbiomaterials.1c00029
Bengtsson-Palme J, Jonsson V, Heß S. (2021). What is the role of the environment in the emergence of novel antibiotic resistance genes? A modelling approach. Environmental Science & Technology. 55(23):15734–15743. https://doi.org/10.1021/acs.est.1c02977
Johansson ML, Calon TGA, Omar O, Shah FA, Trobos M, Thomsen P, Stokroos R, Palmquist A. (2021). Multimodal analysis of the tissue response to a bone-anchored hearing implant: presentation of a two-year case report of a patient with recurrent pain inflammation and infection including a systematic literature review. Front Cell Infect Microbiol - Bacteria and Host. https://doi.org/10.3389/fcimb.2021.640899
Malmberg S, Petrén S, Gunnarsson R, Hedin K, Sundvall PD. (2021). Acute sore throat and Fusobacterium necrophorum in primary healthcare: a systematic review and meta-analysis. BMJ Open. 11(6):e042816. https://doi.org/10.1136/bmjopen-2020-042816
Murphy R, Palm M, Mustonen V, Warringer J, Farewell A, Parts L, Moradigaravand D. (2021). Genomic epidemiology and evolution of Escherichia coli in wild animals in Mexico. MSphere, 6(1). https://doi.org/10.1128/mSphere.00738-20
Svensson Malchau K, Tillander J, Zaborowska M, Hoffman M, Lasa I, Thomsen P, Malchau H, Rolfson O, Trobos M. (2021). Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection. J Orthop Translat. 30:31-40. https://doi.org/10.1016/j.jot.2021.05.008
Burman E, Bengtsson-Palme J (2021). Microbial community interactions are sensitive to small differences in temperature. Frontiers in Microbiology, 12:672910. https://doi.org/10.3389/fmicb.2021.672910
Emgård M, Mwangi R, Mayo C, Mshana E, Nkini G, Andersson R, Msuya SE, Lepp M, Muro F, Skovbjerg S. (2021). Tanzanian primary healthcare workers' experiences of antibiotic prescription and understanding of antibiotic resistance in common childhood infections: a qualitative phenomenographic study. Antimicrob Resist Infect Control. 10(1):94. https://doi.org/10.1186/s13756-021-00952-5
Kalenga TM, Ndoile MM, Munissi JJE, Atilaw Y, Gilissen PJ, Rudenko A, Bourgard C, Sunnerhagen P, Nyandoro SS, Erdelyi M. (2021). Antibacterial biflavonoids from the root bark of Ochna kirkii. Fitoterapia 151:104857. https://doi.org/10.1016/j.fitote.2021.104857
Verheij TJ, Cianci D, van der Velden AW, Butler CC, Bongard E, Coenen S, Colliers A, Francis NA, Little P, Godycki-Cwirko M, Llor C, Chlabicz S, Lionis C, Sundvall PD, Bjerrum L, De Sutter A, Aabenhus R, Harbin NJ, Lindbæk M, Glinz D, Bucher HC, Kovács B, Seifert B, Jurgute RR, Lundgren PT, de Paor M, Matheeussen V, Goossens H, Ieven M. (2021). Clinical presentation, microbiological aetiology and disease course in patients with flu-like illness: a post hoc analysis of randomised controlled trial data. Br J Gen Pract. 72 (716): e217-e224. https://doi.org/10.3399/BJGP.2021.0344
Berglund F, Johnning A, Larsson DGJ, Kristiansson E. (2021). An updated phylogeny of the metallo-β-lactamases. Journal of Antimicrobial Chemotherapy 76(1):117-123. https://doi.org/10.1093/jac/dkaa392
Benkwitz-Bedford S, Palm M, Yasir Demirtas T, Mustonen V, Farewell A, Warringer J, Parts L, Moradigaravand D. (2021). Machine learning prediction of resistance to subinhibitory antimicrobial concentrations from Escherichia coli genomes. mSystems. 6(4):e0034621. https://doi.org/10.1128/mSystems.00346-21
Karami N, Kk S, Yazdanshenas S, Lin YL, Jaén-Luchoro D, Ekedahl E, Parameshwaran S, Lindblom A, Åhrén C, Westerlund F. (2021). Identity of blaCTX-M carrying plasmids in sequential ESBL-E. coli isolates from patients with recurrent urinary tract infections. Microorganisms. 9(6):1138. https://doi.org/10.3390/microorganisms9061138
Kalenga TM, Ndoile MM, Atilaw Y, Gilissen PJ, Munissi JJE, Rudenko A, Bourgard C, Sunnerhagen P, Nyandoro SS, Erdelyi M. (2021). Biflavonoids and chalconoids from the stem bark of Ochna holstii. J. Nat. Prod. 84:364-372. https://doi.org/10.1021/acs.jnatprod.0c01017
Ligouri R, Rommel SH, Bengtsson-Palme J, Helmreich B, Wurzbacher C. (2021). Microbial retention and resistances in stormwater quality improvement devices treating road runoff. FEMS Microbes. 2. https://doi.org/10.1093/femsmc/xtab008
Malmqvist E. (2021). Global health impact: extending access to essential medicines, Nicole Hassoun. Oxford University Press, Economics & Philosophy. https://doi.org/10.1017/S0266267121000134
Hutinel M, Larsson DGJ, Flach C-F. (2021). Antibiotic resistance genes of emerging concern in municipal and hospital wastewater from a major Swedish city. Science of the Total Environment. 812: 151433. https://doi.org/10.1016/j.scitotenv.2021.151433
Larsson DGJ, Flach C-F. (2021). Antibiotic resistance in the environment. Nature Reviews Microbiology. 20:257–269. https://doi.org/10.1038/s41579-021-00649-x Read-only link: https://rdcu.be/cAQBC
Torstensson E, Goyal G, Johnning A, Westerlund F, Ambjörnsson T. (2021). Combining dense and sparse labeling in optical DNA mapping. PloS one 16.11:e0260489. https://doi.org/10.1371/journal.pone.0260489
Maeda G, Gilissen PJ, Rudenko A, van der Wal J, Bourgard C, Gupta AK, Sunnerhagen P, Munissi JJE, Nyandoro SS, Erdélyi M. (2021). Oxygenated cyclohexene derivatives from the stem and root barks of Uvaria pandensis. J. Nat. Prod. 84:3080-3089. https://doi.org/10.1021/acs.jnatprod.1c00811
Birindwa AM, Kasereka JK, Gonzales-Siles L, Geravandi S, Mwilo M, Tudiakwile LK, Mwinja NL, Muhigirwa B, Kashosi T, Manegabe JT, Bugashane EB, Saili SM, Mungo C, Nordén R, Andersson R, Skovbjerg S. (2021). Bacteria and viruses in the upper respiratory tract of Congolese children with radiologically confirmed pneumonia. BMC Infect Dis. 21:837. https://doi.org/10.1186/s12879-021-06570-1
Letara N, Ngocho JS, Karami N, Msuya SE, Nyombi B, Kassam NA, Skovbjerg S, Åhren C, Philemon R, Mmbaga BT. (2021). Prevalence and patient related factors associated with Extended-Spectrum Beta-Lactamase producing Escherichia coli and Klebsiella pneumoniae carriage and infection among pediatric patients in Tanzania. Sci Rep. 23;11(1):22759. https://doi.org/10.1038/s41598-021-02186-2
Umereweneza D, Atilaw Y, Rudenko A, Gütlin Y, Bourgard C, Muhizi T, Sunnerhagen P, Erdélyi M, Gogoll A. (2021). Antibacterial and cytotoxic prenylated dihydrochalcones from Eriosema montanum. Fitoterapia 149:104809. https://doi.org/10.1016/j.fitote.2020.104809
Schar D, Zhao C, Wang Y, Larsson DGJ, Gilbert M, Van Boeckel T. (2021). Twenty-year trends in antimicrobial resistance from aquaculture and fisheries in Asia. Nature Communications. 12:5384. https://doi.org/10.1038/s41467-021-25655-8
Pallon J, Sundqvist M, Rööst M, Danielsson P, Neumark T, Skovbjerg S, Svedin J, Hedin K. (2021). Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare. Infection. 49(4):715-724. https://doi.org/10.1007/s15010-021-01595-9
Harring N, Krockow EM. (2021). The social dilemmas of climate change and antibiotic resistance: an analytic comparison and discussion of policy implications. Humanit Soc Sci Commun 8:125. https://doi.org/10.1057/s41599-021-00800-2
Carlsson F., M. Kataria, E. Lampi, E. Nyberg and T. Sterner (2021), “Red, yellow, or green? Do consumers’ choices of food products depend on the label design? European Review Of Agricultural Economics. jbab036, https://doi.org/10.1093/erae/jbab036
Rodriguez-Molina D, Berglund F, Blaak H, Popa M, Flach C-F, Kemper M, Marutescu L, Pircalabioru G, Spießberger B, Weinmann T, Wengenroth L, Chifiriuc MC, Larsson DGJ, Radon K, Nowak D, Wieser A, Roda de Husman AM, Schmitt H. (2021). Carriage of ESBL-producing Enterobacterales in wastewater treatment plant workers and surrounding residents - The AWARE Study. European Journal of Clinical Microbiology & Infectious Diseases. https://doi.org/10.1007/s10096-021-04387-z
Munthe C, Malmqvist E. (2021). Antibiotikaresistens och socialismens återkomst. Tidskrift för politisk filosofi, 24 (3), 3-17.
Flach C-F, Hutinel M, Razavi M, Åhrén C, Larsson DGJ. (2021). Monitoring of hospital sewage shows both promise and limitations as an early-warning system for carbapenemase-producing Enterobacterales in a low-prevalence setting. Water Research. 200:117261. https://doi.org/10.1016/j.watres.2021.117261
Hutinel M, Fick J, Larsson DGJ, Flach CF. (2021). Investigating the effects of municipal and hospital wastewaters on horizontal gene transfer. Environmental pollution. 276:116733. https://doi.org/10.1016/j.envpol.2021.116733
Kraupner N, Hutinel M, Schumacher K, Gray DA, Genheden M, Fick J, Flach C-F, Larsson DGJ. (2021). Evidence for selection of multi-resistant E. coli by hospital effluent. Environment international. 150:106436. https://doi.org/10.1016/j.envint.2021.106436
Årdal C, Baraldi E, Beyer P, Lacotte Y, Larsson DGJ, Ploy M-C, Røttingen J-A, Smith I. (2020). Supply chain transparency needed to enable sustainable and continuous supply of essential medicines. Bulletin of the World Health Organization. 99:319-320. https://doi.org/10.2471/BLT.20.267724
Munthe C, Fumagalli D, Malmqvist E. (2021). Sustainable healthcare resource allocation, grounding theories and operational principles: response to our commentators. Journal of medical ethics 47(2):90-92. https://doi.org/10.1136/medethics-2021-107299
Wengenroth L, Berglund F, Blaak H, Chifiriuc MC, Flach C-F, Pircalabioru GG, Larsson DGJ, Marutescu L, van Passel M, Popa M, Radon K, de Roda Husman AM, Rodríguez-Molina D, Weinmann T, Wieser A, Schmitt H. antibiotic resistance in wastewater treatment plants and transmission risks for employees and residents: The concept of the AWARE Study. Antibiotics, 10(5):478. https://doi.org/10.3390/antibiotics10050478
Abramova A, Osińska A, Kunche H, Burman E, Bengtsson-Palme J. (2021). CAFE: A software suite for analysis of paired-sample transposon insertion sequencing data. Bioinformatics. 37(1):121–122. https://doi.org/10.1093/bioinformatics/btaa1086
Ebmeyer S, Kristiansson E, Larsson DGJ. (2021). A framework for identifying the recent origins of mobile antibiotic resistance genes. Communications Biology. 4:8. https://doi.org/10.1038/s42003-020-01545-5
Gerner, E, Almqvist S, Thomsen P, Werthén M, Trobos M. (2021). Sodium salicylate influences the Pseudomonas aeruginosa biofilm structure and susceptibility towards silver. Int J Mol Sci. 22(3). https://doi.org/10.3390/ijms22031060

2020

Karkman A, Berglund F, Flach C-F, Kristiansson E, Larsson DGJ. (2020). Predicting clinical resistance prevalence using sewage metagenomic data. Communications Biology. 3:711. https://doi.org/10.1038/s42003-020-01439-6
Dimovska Nilsson K, Grandén J, Farewell A, Fletcher JS. (2020). Interrogation of chemical changes on, and through, the bacterial envelope of Escherichia coli FabF mutant using time‐of‐flight secondary ion mass spectrometry. Surface and Interface Analysis. 53(12):1006-1012. https://doi.org/10.1002/sia.6905
Nijsingh N, Larsson DGJ, de Fine Licht K, Munthe C. (2020). Justifying Antibiotic Resistance Interventions: Uncertainty, Precaution and Ethics. Chapter 22, pp 357-375 In: E. Jamrozik, M. Selgelid (eds.), Ethics and Drug Resistance: Collective Responsibility for Global Public Health, Public Health Ethics Analysis 5. Springer, Cham, https://doi.org/10.1007/978-3-030-27874-8_22
Berglund F, Böhm M, Martinsson A, Ebmeyer S, Österlund T, Johnning A, Larsson, DGJ, Kristiansson E. (2020). Comprehensive screening of genomic and metagenomic data reveals a large diversity of tetracycline resistance genes. Microbial Genomics. 6(11):mgen000455. https://doi.org/10.1099/mgen.0.000455
Nieuwenhuijse D.F, Oude Munnink B.B, Phan M.V.T….Larsson DGJ….et al (ca 100 co-authors) (2020). Setting a baseline for global urban virome surveillance in sewage. Scientific Reports. 10:13748. https://doi.org/10.1038/s41598-020-69869-0
Lampi E, Carlsson F, Sundvall PD, Torres MJ, Ulleryd P, Åhrén C, Jacobsson G. (2020). Interventions for prudent antibiotic use in primary healthcare: An econometric analysis. BMC Health Services Research 20:895. htttps://doi.org/10.1186/s12913-020-05732-2
Kraupner N, Ebmeyer S, Hutinel M, Fick J, Flach C-F, Larsson DGJ. (2020). Selective concentrations for trimethoprim resistance in aquatic environments. Environment international. https://doi.org/10.1016/j.envint.2020.106083
Medlicott K, Wester A, Gordon B, Montgomery M, Tayler E, Sutherland D, Schmoll O, De Souza M, Koo-Oshima S, DaBalogh K, Pinto Ferreira J, Erlacher-Vindel E, Clayton H, Graham D, Larsson DGJ, Medema G, Roda de Husman AM, Schmitt H, Yang M, Zhang Y. (2020). Technical Brief on water, sanitation, hygiene and wastewater management to prevent infections and reduce the spread of antimicrobial resistance. Report number: ISBN: 978-92-4-000641-6Affiliation: World Health Organization WHO. https://www.who.int/water_sanitation_health/publications/wash-wastewater-management-to-prevent-infections-and-reduce-amr/en/
Alalam H, Graf FE, Palm M, Abadikhah M, Zackrisson M, Boström J, Fransson A, Hadjineophytou C, Persson L, Stenberg S, Mattsson M, Ghiaci P, Sunnerhagen P, Warringer J, Farewell A. (2020). A High-Throughput Method for Screening for Genes Controlling Bacterial Conjugation of Antibiotic Resistance. mSystems. https://doi.org/10.1128/mSystems.01226-20
Gonzales-Siles L, Karlsson R, Schmidt P, Salvà-Serra F, Jaén-Luchoro D, Skovbjerg S, Moore ERB, Gomila M. (2020). A Pangenome Approach for Discerning Species-Unique Gene Markers for Identifications of Streptococcus pneumoniae and Streptococcus pseudopneumoniae. Front. Cell Infect. Microbiol. 10:222. https://doi.org/10.3389/fcimb.2020.00222
Grevskott DH, Salvà-Serra F, Moore ERB, Marathe NP. (2020). Nanopore sequencing reveals genomic map of CTX-M-type extended-spectrum β-lactamases carried by Escherichia coli strains isolated from blue mussels (Mytilus edulis) in Norway. BMC Microbiology. 20. https://doi.org/10.1186/s12866-020-01821-8
Jaén-Luchoro D, Busquets A, Karlsson R, Salvà-Serra F, Åhrén C, Karami N, Moore ERB. (2020). Genomic and proteomic characterization of the extended-spectrum β-lactamase (ESBL)-producing Escherichia coli strain CCUG 73778: a virulent, nosocomial outbreak strain. Microorganisms. 8(6):893. https://doi.org/10.3390/microorganisms8060893
Birindwa AM, Manegabe JT, Mindja A, Nordén R, Andersson R, Skovbjerg S. (2020). Decreased number of hospitalized children with severe acute lower respiratory infection after introduction of the pneumococcal conjugate vaccine in the Eastern Democratic Republic of the Congo. Pan African Medical Journal 37: 211. https://doi.org/10.11604/pamj.2020.37.211.22589
Malmqvist E, Munthe C. (2020). What high-income states should do to address industrial antibiotic pollution. Public Health Ethics. 13(3):275–287. https://doi.org/10.1093/phe/phaa020
Buongermino Pereira M, Österlund T, Eriksson KM, Backhaus T, Axelson-Fisk M and Kristiansson E. (2020). A comprehensive survey of integron-associated genes present in metagenomes. BMC Genomics 21:495. https://doi.org/10.1186/s12864-020-06830-5
Jaén-Luchoro D, Gonzales-Siles L, Karlsson R, Svensson-Stadler L, Molin K, Cardew S, Jensie-Markopolous S,Ohlén M, Inganäs E, Skovbjerg S, Tindalle BJ, Moore ERB. (2020). Corynebacterium sanguinis sp. nov., a clinical and environmental associated corynebacterium. Systematic and Applied Microbiology, 43. https://doi.org/10.1016/j.syapm.2019.126039
Müller V, Nyblom M, Johnning A, Wrande M, Dvirnas A, Sriram KK, Giske CG, Ambjörnsson T, Sandegren L, Kristiansson E, Westerlund F. (2020). Cultivation-free typing of bacteria using optical dna mapping. ACS Infec Dis, 6. https://doi.org/10.1021/acsinfecdis.9b00464
Berglund F, Johnning A, Larsson, DGJ Kristiansson, E. (2020). The evolutionary history of the metallo-beta-lactamases. Journal of Antimicrobial Chemotherapy. https://doi.org/10.1093/jac/dkaa392
Zaborowska M, Taulé Flores C, Vazirisani F, Thomsen P, Trobos M. (2020). Extracellular vesicles influence the growth and adhesion of Staphylococcus epidermidis under antimicrobial selective pressure. Front Microbiol. https://doi.org/10.3389/fmicb.2020.01132
Gerner E, Almqvist S, Werthen M, Trobos M. (2020). Sodium salicylate interferes with quorum-sensing-regulated virulence in chronic wound isolates of Pseudomonas aeruginosa in simulated wound fluid. J Med Microbiol 69(5). https://doi.org/10.1099/jmm.0.001188
Mamedov I, Naghiyev F, Maharramov A, Uwangue O, Farewell A, Sunnerhagen P, Erdelyi M. (2020). Antibacterial activity of 2-amino-3-cyanopyridine derivatives. Mendeleev Commun. 30. https://doi.org/10.1016/j.mencom.2020.07.031
Razavi M, Flach C-F, Kristiansson E, Larsson DGJ. (2020). The association between insertion sequences and antibiotic resistance genes. mSphere. https://doi.org/10.1128/mSphere.00418-20
Zhang T, Fukuda K, Topp E, Zhu Y-G, Smalla K, Tiedje JM, Larsson DGJ. (2020). Editorial: The Environmental Dimension of Antibiotic Resistance, FEMS Microbiology Ecology, 96 (8):fiaa130. https://doi.org/10.1093/femsec/fiaa130.
Leiros H-K S, Thomassen A M, Samuelsen Ø, Flach C-F, Kotsakis S D, Larsson DGJ. (2020). Structural insight to the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10. FEBS Open Bio. https://doi.org/10.1002/2211-5463.12935
Salvà-Serra F, Jaén-Luchoro D, E. Jakobsson H, Gonzales-Siles L, Karlsson R, Busquets A, Gomila M, Bennasar-Figueras A, Russell JE, Abbas Fazal M, Alexander S, Moore ERB. (2020). Complete genome sequences of Streptococcus pyogenes type strain reveal 100%-match between PacBio-solo and Illumina-Oxford Nanopore hybrid assemblies. Scientific Reports. https://doi.org/10.1038/s41598-020-68249-y
Kvint K, Palm M, Farewell A. (2020). Teaching about antibiotic resistance to a broad audience: a multidisciplinary approach. FEMS Microbiology Letters. https://doi.org/10.1093/femsle/fnaa111
Fröhlich C, Sörum V, Huber S, Samuelsen Ö, Berglund F, Kristiansson E, Kotsakis S, Marathe NP, Larsson DGJ, Leiros H-K S. (2020). Structural and biochemical characterization of the environmental metallo-β-lactamases MYO-1, ECV-1 and SHD-1. J Antimicrob Chemother. 1https://doi.org/10.1093/jac/dkaa175
Nijsingh N, Christian Munthe C, Lindblom A, Christina Åhrén. (2020). Screening for multi-drug-resistant Gram-negative bacteria: what is effective and justifiable? Monash Bioethics Review. https://doi.org/10.1007/s40592-020-00113-1
Davis M, Lyall B, Whittaker A, Lindgren M, Djerf-Pierre M, Flowers P. (2020). A year in the public life of superbugs: News media on antimicrobial resistance and implications for health communications. Social Science & Medicine, 256. https://doi.org/10.1016/j.socscimed.2020.113032
Tamire M, Addissie A, Kumie A, Husmark E, Skovbjerg S, Andersson R, Lärstad M. (2020). Respiratory Symptoms and Lung Function among Ethiopian Women in Relation to Household Fuel Use. Int J Env Res Pub Health. https://www.mdpi.com/1660-4601/17/1/41/pdf
Böhm M-E, Razavi M, Flach C-F, Larsson DGJ. (2020). A novel, integron-regulated class C β-lactamase. Antibiotics. https://doi.org/10.3390/antibiotics9030123
Eckert EM, Di Cesare A, Fontaneto D, Berendonk TU, Bürgmann H, Cytryn E, Fatta-Kassinos D, Franzetti A, Larsson DGJ, Manaia CM, Pruden A, Singer AC, Udikovic-Kolic N, Corno G. (2020). Every fifth published metagenome is not available to science. PloS Biology. https://doi.org/10.1371/journal.pbio.3000698
Huijbers PMSC, Larsson DGJ, Flach C-F. (2020). Surveillance of antibiotic resistant Escherichia coli in human populations through urban wastewater in ten European countries. Environmental Pollution. https://doi.org/10.1016/j.envpol.2020.114200
Snygg-Martin U, Ruus C, Skovbjerg S, Studahl M, Andersson LM. (2020). Does extraction of cardiac implantable electronic devices improve outcome in patients with Staphylococcus aureus bacteraemia? Infect Dis (Lond). 52(12) https://doi.org/10.1080/23744235.2020.1799070
Gunnarsson RK, Manchal N. (2020). Group C beta hemolytic Streptococci as a potential pathogen in patients presenting with an uncomplicated acute sore throat – a systematic literature review and meta-analysis. Scandinavian Journal of Primary Health Care. https://doi.org/10.1080/02813432.2020.1753374
Böhm M-E, Razavi M, Marathe NP, Flach C-F, Larsson DGJ. (2020). Discovery of a novel integron-borne aminoglycoside resistance gene present in clinical pathogens by screening environmental bacterial communities. Microbiome. https://doi.org/10.1186/s40168-020-00814-z.
Laxminarayan R, Van Boeckel T, Frost I, Kariuki S, Khan E, Limmathurotsakul D, Larsson DGJ, Levy-Hara G, Mendelson M, Outterson K, Peacock S, Zhu Y-G. (2020). The Lancet Infectious Diseases Commission on antimicrobial resistance: six years later. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30003-7
Bengtsson-Palme J. (2020). Microbial model communities: To understand complexity, harness the power of simplicity. Comput Struct Biotechnol J. https://doi.org/10.1016/j.csbj.2020.11.043
Karlsson R, Thorsell A, Gomila M, Salvà-Serra F, Jakobsson HE, Gonzales-Siles L, Jaén-Luchoro D, Skovbjerg S, Fuchs J, Karlsson A, Boulund F, Johnning A, Kristiansson E, Moore ERB. (2020). Discovery of species-unique peptide biomarkers of bacterial pathogens by tandem mass spectrometry-based proteotyping. Mol & Cell Proteomics, 19. https://doi.org/10.1074/mcp.RA119.001667
Bengtsson-Palme J, Heß S. (2020). Strategies to reduce or eliminate resistant pathogens in the environment. In: Capelo Martinez JL, Igrejas G (Eds.) Antibiotic Drug Resistance, 637–673. Wiley, NJ, USA. https://doi.org/10.1002/9781119282549.ch24
Maeda G, van der Wal J, Gupta AK, Munissi JJE, Orthaber A, Sunnerhagen P, Nyandoro SS, Máté Erdélyi M. (2020). Oxygenated Cyclohexene Derivatives and Other Constituents from the Roots of Monanthotaxis trichocarpa. J Nat Prod, 83. https://doi.org/10.1021/acs.jnatprod.9b00363
Rutgersson C, Ebmeyer S, Lassen SB, Karkman A, Fick J, Kristiansson K, Brandt KK, Flach C-F, Larsson DGJ. (2019). Long-term application of Swedish sewage sludge on farmland does not cause clear changes in the soil bacterial resistome. Environ Int. 137:105339. https://doi.org/10.1016/j.envint.2019.105339

2019

Nijsingh N, Munthe C, Larsson DGJ (2019). Managing pollution from antibiotics manufacturing: charting actors, incentives and disincentives. Environmental Health 18, (95): https://doi.org/10.1186/s12940-019-0531-1
Skoog Ståhlgren G, Tyrstrup M, Edlund C, Giske CG, Mölstad S, Norman C, Rystedt K, Sundvall PD, Hedin K. (2019). Penicillin V four times daily for five days versus three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci: randomised controlled, open label, non-inferiority study. BMJ. 367:l5337. https://doi.org/10.1136/bmj.l5337
Emgård M, Msuya SE, Nyombi BM, Mosha D, Gonzales-Siles L, Nordén R, Geravandi S, Mosha V, Blomqvist J, Franzén S, Sahlgren F, Andersson R, Skovbjerg S. (2019). Carriage of penicillin non-susceptible pneumococci among children in northern Tanzania in the 13-valent pneumococcal vaccine era. Int J Infect Dis. 81:156-166. https://doi.org/10.1016/j.ijid.2019.01.035
Marathe NP, Salvà-Serra F, Karlsson R, Larsson DGJ, Moore ERB, Svensson-Stadler L, Jakobsson HE. (2019). Scandinavium goeteborgense gen. nov., sp. nov., a new member of the family Enterobacteriaceae isolated from a wound infection, carries a novel quinolone resistance gene variant. Front Microbiol. 10:2511. https://doi.org/10.3389/fmicb.2019.02511
Carlsson F, Jacobssonb G, Jagers S, Lampi E, Robertson F, Rönnerstrand B. (2019). Who is willing to stay sick for the collective? – Individual characteristics, experience, and trust. SSM Popul Health. 9:100499. https://doi.org/10.1016/j.ssmph.2019.100499
Heß S, Kneis D, Österlund T, Li B, Kristiansson E, Berendonk TU. (2019). Sewage from airplanes exhibits high abundance and diversity of antibiotic resistance genes. Environ Sci Technol. 53, 23, 13898–13905. https://doi.org/10.1021/acs.est.9b03236
Ebmeyer S, Kristiansson E, Larsson DGJ. (2019). The mobile FOX AmpC beta-lactamases originated in Aeromonas allosaccharophila. Int J Antimicrob Agents. 54(6):798-802. https://doi.org/10.1016/j.ijantimicag.2019.09.017
Munthe C, Nijsingh N, de Fine Lich K, Larsson DGJ. (2019). The ethics of antibiotic resistance: towards an agenda for feasible and justified global health policy. Bioethics. 33(7):731-733. https://doi.org/10.1111/bioe.12655
Nilsson KD, Palm M, Hood J, Sheriff J, Farewell A, Fletcher JS. (2019). Chemical changes on, and through, the bacterial envelope in Escherichia coli mutants exhibiting impaired plasmid transfer identified using time-of-flight secondary ion mass spectrometry. Anal. Chem. 91, 17, 11355–11361. https://doi.org/10.1021/acs.analchem.9b02533
Bengtsson-Palme J, Milakovic M, Švecová H, Ganjto M, Jonsson V, Grabic R, Udiković Kolić N. (2019). Industrial wastewater treatment plant enriches resistance genes and alter the structure of microbial communities. Water Research, 162, 437-445. 1https://doi.org/10.1016/j.watres.2019.06.073
Monjas L, Fodran P, Kollback J, Cassani C, Olsson T, Genheden M, Larsson DGJ, Wallentin C-J. (2019). Synthesis and biological evaluation of truncated derivatives of abyssomicin C as antibacterial agents. Beilstein J. Org. Chem. 15:1468–1474. 1https://doi.org/10.3762/bjoc.15.147
Davies JS, Coombes D, Horne CR, Pearce FG, Friemann R, North RA, Dobson RCJ. (2019). N-Acetylglucosamine-6-phosphate deacetylase and glucosamine-6-phosphate deacetylase from Staphylococcus aureus: Function and solution structure studies, FEBS Lett. 1https://doi.org/10.1002/1873-3468.13289
Ruppé E, Bengtsson-Palme J, Charretier Y, Schrenzel J. (2019). How next-generation sequencing can address the antimicrobial resistance challenge. AMR Control. 2019-20, 60-65. Link to paper.
Marathe NP, Berglund F, Razavi M, Pal C, Dröge J, Samant S, Kristiansson E, Larsson DGJ. (2019). Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes. Microbiome. 7:97. https://doi.org/10.1186/s40168-019-0710-x
Huijbers PMC, Flach C-F, Larsson DGJ. (2019). A conceptual framework for the environmental surveillance of antibiotics and antibiotic resistance. Environ Int. 130:104880. https://doi.org/10.1016/j.envint.2019.05.074
Ljungström L, Andersson R, Jacobsson G. (2019). Incidences of community onset severe sepsis, Sepsis-3 sepsis, and bacteremia in Sweden - a prospective population-based study. PLOS One. 14(12): e0225700. https://doi.org/10.1371/journal.pone.0225700
Bengtsson-Palme J. (2019). Assessment and management of risks associated with antibiotic resistance in the environment. In: Roig B, Weiss K, Thoreau V (Eds.) Management of emerging public health issues and risks: multidisciplinary approaches to the changing environment, 243–263. Elsevier, UK. https://doi.org/10.1016/B978-0-12-813290-6.00010-X
Rönnerstrand, B. (2019). Dystopiernas kamp: svenskarnas syn på klimatförändringar och antibiotikaresistens i jämförelse i Ulrika Andersson, Björn Rönnerstrand, Patrik Öhberg & Annika Bergström (red) Storm och stiltje. 1 Göteborgs universitet: SOM-institutet.
Hendriksen RS, Munk P, Niage P, van Bunnik B,…., Larsson DGJ,….(ca 100 co-authors). (2019). Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. Nature communications 10, 1124. https://doi.org/10.1038/s41467-019-08853-3
Berglund F, Österlund T, Boulund F, Marathe NP, Larsson DGJ, Kristiansson E. (2019). Identification and reconstruction of novel antibiotic resistance genes from metagenomes. Microbiome. 7:52. https://doi.org/10.1186/s40168-019-0670-1
Pippione AC, Sainas S, Goyal P, Fritzson I, Cassiano GC, Giraudo A, Giorgis M, Tavella TA, Bagnati R, Rolando B, Caing-Carlsson R, Costa FTM, Andrade CH, Al-Karadaghi S, Boschi D, Friemann R, Lolli ML. (2019). Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: synthesis, biological evaluation and X-ray structural studies, Eur J Med Chem, 163:266-280. https://doi.org/10.1016/j.ejmech.2018.11.044
Durán RE, Méndez V, Rodríguez-Castro L, Barra-Sanhueza B, Salvá-Serra F, Moore ERB, Castro-Nallar E, Seeger M. (2019). Genomic and physiological traits of the marine bacterium Alcaligenes aquatilis QD168 isolated from quintero bay, central chile, reveal a robust adaptive response to environmental stressors. Front. Microbiol. 10:528. https://doi.org/10.3389/fmicb.2019.00528
Djerf-Pierre M, Lindgren, M, Budinski, M A. (2019). The role of journalism on YouTube: Audience engagement with ’Superbug’ reporting. Media and Communication 7(1): 235-247. https://doi.org/10.17645/mac.v7i1.1758
Guzman-Otazo J, Gonzales-Siles L, Poma V, Bengtsson-Palme J, Thorell K, Flach CF, Iñiguez V, Sjöling Å. (2019). Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia. PLoS ONE. 14(1): e0210735. https://doi.org/10.1371/journal.pone.0210735
Munthe C, Nijsingh N, de Fine Licht K, Larsson DGJ. (2019). Health-related research ethics and social value: antibiotic resistance intervention research and pragmatic risks. Bioethics, 2019;33:335–342. https://doi.org/10.1111/bioe.12580
Karkman A, Pärnänen K, DGJ Larsson. (2019). Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments. Nature Communications. 80:10. https://www.nature.com/articles/s41467-018-07992-3
Munthe C, Nijsingh N (2019). Cutting red tape to manage drastic public health threats: Should antimicrobial drug innovation be expedited. Bioethics 33(7):785-791. https://doi.org/10.1111/bioe.12605
Ebmeyer S, Kristiansson E, Larsson DGJ. (2019). PER extended-spectrum beta-lactamases originate from Pararheinheimera spp. J Antimicrobial Agents. 53:158 https://doi.org/10.1016/j.ijantimicag.2018.10.019.

2018

Karlsson R, Gonzales-Siles L, Gomila M, Busquets A, Salvà-Serra F, Jaén-Luchoro D, Jakobsson E H, Karlsson A, Boulund F, Kristiansson E, Moore ERB. (2018). Proteotyping bacteria: Characterization, differentiation and identification of pneumococcus and other species within the Mitis Group of the genus Streptococcus by tandem mass spectrometry proteomics. PLoS One. https://doi.org/10.1371/journal.pone.0208804
Aga D, Davies J, Gandra S, Kasprzyk B, DGJ Larsson, McLain J, Singer A, Snape J, Slijkhuis H, Sweetman A, Voulvoulis N. (2018). Antimicrobial manufacturing waste. Pages 30-45. In: Initiatives for Addressing Antimicrobial Resistance in the Environment: Current Situation and Challenges. https://wellcome.ac.uk/sites/default/files/antimicrobial-resistance-environment-report.pdf
Jonsson V, Österlund T, Nerman O, Kristiansson E. (2018). Modelling of zero-inflation improves inference of metagenomic gene count data. Stat Methods Med Res. 28(12):3712-3728. https://doi.org/10.1177/0962280218811354
Johnning A, Karami N, Tång Hallbäck E, Müller V, Nyberg L, Buongermino Pereira M, Stewart C, Ambjörnsson T, Westerlund F, Adlerberth I, Kristiansson E. (2018). The resistomes of six carbapenem-resistant pathogens – a critical genotype–phenotype analysis. Microbial Genomics. 4(11). https://doi.org/10.1099/mgen.0.000233
Munthe, C, El-Alti, L, Hartvigsson, T, Nijsingh, N (2018). Disputing with patients in person-centered care: Ethical aspects in standard care, pediatrics, psychiatry, and public health. Journal of Argumentation in Context 7(2): 233-246. https://doi.org/10.1075/jaic.18022.mun
Kotsakis S, Flach CF, Razavi M, Larsson DGJ. (2018). Characterization of the first OXA-10 natural variant with increased carbapenemase activity. Antimicrobial Agents and Chemotherapy. https://aac.asm.org/content/early/2018/10/31/AAC.01817-18.long
Karp J, Edman-Wallér J, Toepfer M, Lundqvist A, G Jacobsson. (2018). Clostridioides difficile incidence related to in-hospital cephalosporin use: a tale of two highly comparable hospitals. J Antimicrob Chemother. https://doi.org/10.1093/jac/dky408
Graf FE, Palm M, Warringer J, Farewell A. (2018). Inhibiting conjugation as a tool in the fight against antibiotic resistance. Drug development research. https://doi.org/10.1002/ddr.21457
Pärnänen K, Karkman A, Hultman J, Lyra C, Bengtsson-Palme J, Larsson DGJ, Rautava S, Salminen S, Kumar H, Satokari R, Isolauri E, Virta M. (2018). Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements. Nature Communications. https://doi.org/10.1038/s41467-018-06393-w
Flach CF, Genheden M, Fick J, DGJ Larsson. (2018). A comprehensive screening of E. coli isolates from Scandinavia’s largest sewage treatment plant indicates no selection for antibiotic resistance. Environmental Science & Technology. 52, 19, 11419–11428. https://doi.org/10.1021/acs.est.8b03354
Bengtsson-Palme, J. (2018). The diversity of uncharacterized antibiotic resistance genes can be predicted from known gene variants—but not always. Microbiome. 6:125. https://doi.org/10.1186/s40168-018-0508-2
Birindwa AM, Emgård M, Nordén R, Samuelsson E, Geravandi S, Gonzales-Siles L, Muhigirwa B, Kashosi T, Munguakonkwa E, Manegabe JT, Cibicabene D, Morisho L, Mwambanyi B, Mirindi J, Kabeza N, Lindh M, Andersson R, Skovbjerg S. (2018). High rate of antibiotic resistance among pneumococci carried by healthy children in the eastern part of the Democratic Republic of the Congo. BMC Pediatrics. 18:361 https://rdcu.be/bbLnV
Bahram M, Hildebrand F, Forslund SK, Anderson JL, Soudzilovskaia NA, Bodegom PM, Bengtsson-Palme J, Anslan S, Coelho LP, Harend H, Huerta-Cepas J, Medema MH, Maltz MR, Mundra S, Olsson PA, Pent M, Põlme S, Sunagawa S, Ryberg M, Tedersoo L, Bork P. (2018). Structure and function of the global topsoil microbiome. Nature. https://doi.org/10.1038/s41586-018-0386-6
Walujkar SA, Kumbhare SV, Marathe NP, Patangia DV, Lawate PS, Bharadwaj RS, Shouche YS. (2018). Molecular profiling of mucosal tissue associated microbiota in patients manifesting acute exacerbations and remission stage of ulcerative colitis. World J Microbiol Biotechnol. 34:76. https://doi.org/10.1007/s11274-018-2449-0
Lindblom A, Sriram KK, Müller V, Öz R, Sandström H, Åhrén C, Westerlund F, Karami N. (2018). Interspecies plasmid migration appears rare in sequential infections with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Diagn Microb Inf Dis. https://doi.org/10.1016/j.diagmicrobio.2018.10.014
Thomsen H, Graf FE, Farewell A, Ericson MB. (2018). Exploring photoinactivation of microbial biofilms using laser scanning microscopy and confined 2-photon excitation. J Biophotonics.11(10):e201800018. https://doi.org/10.1002/jbio.201800018
Kapla M, Munthe C, Rönnerstrand B, Svensson J, Vedinelli C. (2018). Antibiotikaresistens – hoten och vägen framåt. PODD, Ord & Bild, October 22, 2018. Online: http://www.tidskriftenordobild.se/ordoblogg/category/podd-om-antibiotikaresistens
Lindgren Å, Karami N, Karlsson R, Åhrén C, Welker M, Moore ERB, Stadler LS. (2018). Development of a rapid MALDI-TOF MS based epidemiological screening method using MRSA as a model organism. Eur J Clin Microbiol Infect Dis. https://doi.org/10.1007/s10096-017-3101-x
Moradigaravand D, Palm M, Farewell A, Mustonen V, Warringer J, Parts L. (2018). Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences. CSH bioRxi https://doi.org/10.1101/338194
Larsson DGJ, Andremont A, Bengtsson-Palme J, Koefoed Brandt K, de Roda Husman AM, Fagerstedt P, Fick J, Flach CF, Gaze WH, Kuroda M, Kvint K, Laxminarayan R, Manaia CM, Nielsen KM, Plant L, Ploy MC, Segovia C, Simonet P, Smalla K, Snape J, Topp E, van Hengel A, Verner-Jeffreys DW, Virta MPJ, Wellington EM, Wernersson AS. (2018). Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance. Environ Int. 117:132-138. https://doi.org/10.1016/j.envint.2018.04.041
Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R. (2018). Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site. Nat Commun. 1;9(1):1753. https://doi.org/10.1038/s41467-018-04045-7
Kraupner N, Ebmeyer S, Bengtsson-Palme J, Fick J, Kristiansson E, Flach C-F, Larsson DGJ. (2018). Selective concentration for ciprofloxacin resistance in Escherichia coli grown in complex aquatic bacterial biofilms. Environ Int. 116:255-268. https://doi.org/10.1016/j.envint.2018.04.029
Lindblom A, Karami N, Magnusson T, Åhrén C. (2018). Subsequent infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in patients with prior infection or fecal colonization. Eur J Clin Microbiol Infect Dis. https://doi.org/10.1007/s10096-018-3275-x
Pereira MB, Wallroth M, Jonsson V, Kristiansson E. (2018). Comparison of normalization methods for the analysis of metagenomic gene abundance data, BMC Genomics 19(274). https://doi.org/10.1186/s12864-018-4637-6
Munthe C, El-Alti L, Hartvigsson T, Nijsingh N (2018). Disputing with patients in person-centered care: ethical aspects in standard care, pediatrics, psychiatry, and public health. Journal of Argumentation in Context. 7(2):235-244. https://doi.org/ 10.1075/jaic.18022.mun
Topp E, Larsson DGJ, Miller DN, Van den Eede C, Virta MPJ. (2018). Antimicrobial resistance and the environment: assessment of advances, gaps and recommendations for agriculture, aquaculture and pharmaceutical manufacturing. FEMS Microbiol Ecol. 94(3). https://doi.org/10.1093/femsec/fix185
Marathe NP, Janzon A, Kotsakis SD, Flach C-F, Razavi M, Berglund F, Kristiansson E, Larsson DGJ. (2018). Functional metagenomics reveals a novel carbapenem-hydrolyzing mobile beta-lactamase from Indian river sediments contaminated with antibiotic production waste. Environ Int. 112:279-286. https://doi.org/10.1016/j.envint.2017.12.036
Thomsen H, James J, Farewell A, M.B. Ericson. (2018). Spatially confined photoinactivation of bacteria: towards novel tools for detailed mechanistic studies. SPIE proc 10498. https://doi.org/10.1117/12.2290718
Alalam H, Graf FE, Palm M, Abadikhah M, Zackrisson M, Mattsson M, Hadjineophytou C, Persson L, Stenberg S, Ghiaci P, Sunnerhagen P, Warringer J, Farewell A. (2018). Conjugation factors controlling F-plasmid antibiotic resistance transmission. CSH bioRxi. https://doi.org/10.1101/271254
Robertson F, Jagers S, Rönnerstrand B. (2018). Managing sustainable use of antibiotics—the role of trust. Sustainability. https://doi.org/10.3390/su10010143
Nijsingh N. (2018) "Antibiotica-resistentie: een complexe catastrofe”, Podium voor Bio-Ethiek, 24(2): 20-22.
Larsson DGJ. (2018). Risks of using the natural defense of commensal bacteria as antibiotics call for research and regulation. Int J Antimicrob Agents. https://doi.org/10.1016/j.ijantimicag.2017.12.018
Bengtsson-Palme J, Gunnarsson L, Larsson DGJ. (2018). Can branding and price of pharmaceuticals guide informed choices towards improved pollution control during manufacturing? J Clean Prod. 171:137 https://doi.org/10.1016/j.jclepro.2017.09.247
Bengtsson-Palme J, Larsson DGJ. (2018). Protection goals must guide risk assessment for antibiotics. Environment international. In press. https://doi.org/10.1016/j.envint.2017.10.019
Bengtsson-Palme J, Kristiansson E, Larsson DGJ. (2018). Environmental factors influencing the development and spread of antibiotic resistance. FEMS Micro Rev. 1;42. https://doi.org/10.1093/femsre/fux053

2017

Razavi M, Marathe NP, Gillings MR, Flach CF, Kristiansson E, Larsson DGJ. (2017). Discovery of the fourth mobile sulfonamide resistance gene. Microbiome. 5:160. https://doi.org/10.1186/s40168-017-0379-y
Mölstad S, Löfmark S, Carlin K, Erntell M, Aspevall O, Blad L, Hanberger H, Hedin K, Hellman J, Norman C, Skoog G, Stålsby-Lundborg C, Tegmark Wisell K, Åhrén C, Cars O. (2017) Lessons learnt during 20 years of the Swedish strategic programme against antibiotic resistance. Bull World Health Organ. 2017:95(11):764-773. https://doi.org/10.2471/BLT.16.184374
North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P, Wahlgren WY, Ramaswamy S, Friemann R, Dobson RCJ. (2017). "Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes. Biophys Rev. Dec 8. https://doi.org/10.1007/s12551-017-0343-x
Jutkina J, Marathe NP, Flach C-F, Larsson DGJ. (2017). Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations. Sci Total Environ. Nov 4;616-617:172-178. https://doi.org/10.1016/j.scitotenv.2017.10.312
Ljungström L, Pernestig A-K, Jacobsson G, Andersson R, Usener B, Tilevik D. (2017). Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsis. PLoS ONE 12(7): e0181704. https://doi.org/10.1371/journal.pone.0181704
Berglund F, Nachiket MP, Österlund T, Bengtsson-Palme J, Kotsakis S, Flach CF, Larsson DGJ, Kristiansson E. (2017). Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data. Microbiome. 5:134. https://doi.org/10.1186/s40168-017-0353-8
Lindgren Å, Karami N, Karlsson R, Åhrén C, Welker M, Moore ERB, Stadler LS. (2017). Development of a rapid MALDI-TOF MS based epidemiological screening method using MRSA as a model organism. Eur J Clin Microbiol Infect Dis. Sep 18. https://doi.org/10.1007/s10096-017-3101-x
Boulund F, Berglund F, Flach C-F, Bengtsson-Palme J, Marathe NP, Larsson DGJ, Kristiansson E. (2017). Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets. BMC Genomics 18:682
https://doi.org/10.1186/s12864-017-4064-0
Djerf-Pierre M, Shehata A. (2017) Medierna och människors oro för antibiotikaresistens. Larmar och gör sig till. 169-186. SOM-institutets böcker. ISBN 978-91-89673-39-7.
Marathe N, Pal C, Gaikwad S, Jonsson V, Kristiansson E, DGJ Larsson. (2017). Untreated urban waste contaminates Indian river sediments with resistance genes to last resort antibiotics. Water Res. Nov 1(124):388-397. https://doi.org/10.1016/j.watres.2017.07.060
Bengtsson-Palme J., Larsson DGJ., Kristiansson E. (2017). Using metagenomics to investigate human and environmental resistomes. J Antimicrob Chemother. https://doi.org/10.1093/jac/dkx199
Alsterholm M, Strömbeck L, Ljung A, Karami N, Widjestam J, Gillstedt M, Åhren C and Faergemann J. (2017). Variation in Staphylococcus aureus Colonization in Relation to Disease Severity in Adults with Atopic Dermatitis during a Five-month Follow-up. Acta Derm Venereol. Jul 6;97(7):802-807. https://doi.org/10.2340/00015555-2667
Davis M, Whittaker A, Lindgren M, Djerf-Pierre M, Manderson L, Flowers P. (2017). Understanding media publics and the antimicrobial resistance crisis. Global Public Health. 13(9): 1158-1168. https://doi.org/10.1080/17441692.2017.1336248
Boulund F, Karlsson R, Gonzales-Siles L, Johnning A, Karami N, Al-Bayati O, Åhrén C, Moore ERB, Kristiansson E. (2017). Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics. Mol Cell Proteomics. Jun;16(6):1052-1063. https://doi.org/10.1074/mcp.M116.061721
Ljungström LR, Jacobsson G, Claesson BEB, Andersson R, Enroth H. (2017). Respiratory viral infections are underdiagnosed in patients with suspected sepsis. Eur J Clin Microbiol Infect Dis. 36:1767–1776. https://doi.org/10.1007/s10096-017-2990-z
Jakobsson HE, Salvà-Serra F, Thorell K, Karlsson R, Gonzales-Silès L, Boulund F, Engstrand L, Kristiansson E, Moore ER. (2017). Draft genome sequences of six strains of Streptococcus pneumoniae from serotypes 5, 6A, 6B, 18C, 19A, and 23F. Genome Announc. 5(14):e00125-17. https://doi.org/10.1128/genomeA.00125-17
Bengtsson-Palme J. (2017). Antibiotic resistance in the food supply chain: Where can sequencing and metagenomics aid risk assessment? Curr Opin Food Sci. 14:66–71. https://doi.org/10.1016/j.cofs.2017.01.010
Flach CF, Pal C, Svensson CJ, Kristiansson E, Östman M, Bengtsson-Palme J, Tysklind M, Larsson DGJ. (2017). Does antifouling paint select for antibiotic resistance? Science of the Total Environment. 590–591:461–468. https://doi.org/10.1016/j.scitotenv.2017.01.213
Hao X*, Li X*, Pal C*, Hobman J, Rosen BP, Larsson DGJ, Saquib Q, Alwathnani HA, Zhu Y-G, Rensing C. (2017). Bacterial resistance to arsenic protects against protist killing. Biometals. Biometals. 30(2):307–311. https://doi.org/10.1007/s10534-017-0003-4 (*-co-first authors).
Pal C, Asiani K, Arya S, Rensing C, Stekel DJ, Larsson DGJ, Hobman JL. (2017). Metal resistance and its association with antibiotic resistance. Advances in Microbial Physiology. Volume 70, Chapter 7, Pages 261-313. ISBN: 9780128123867.
Helldal L, Karami N, Welinder-Olsson C, Moore ER, Åhren C. (2017). Evaluation of MLVA for epidemiological typing and outbreak detection of ESBL-producing Escherichia coli in Sweden. BMC Microbiol. 17(1):8. https://doi.org/10.1186/s12866-016-0922-1
Rönnerstrand B, Lapurente V. (2017). Corruption and use of antibiotics in regions of Europe. Health Policy. 121(3):250-256. https://doi.org/10.1016/j.healthpol.2016.12.010
Gumpert H, Kubicek-Sutherland JZ, Porse A, Karami N, Munck C, Linkevicius M, Adlerberth I, Wold AE, Andersson DI, Sommer MOA. (2017). Transfer and persistence of a multi-drug resistance plasmid in situ of the infant gut microbiota in the absence of antibiotic treatment. Front Microbiol. 8:1852. https://doi.org/10.3389/fmicb.2017.01852

2016

Ballard MS, Schønheyder HC, Knudsen JD, Lyytikäinen O, Dryden M, Kennedy KJ, Valiquette L, Pinholt M, Jacobsson G, Laupland KB; International Bacteremia Surveillance Collaborative. (2016). The changing epidemiology of group B streptococcus bloodstream infection: a multi-national population-based assessment. Infect Dis (Lond). 48(5):386-91. https://doi.org/10.3109/23744235.2015.1131330
North RA, Watson AJ, Pearce FG, Muscroft-Taylor AC, Friemann R, Fairbanks AJ, Dobson RC. (2016). Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett. 590(23):4414-4428. https://doi.org/10.1002/1873-3468.12462
Bengtsson-Palme J, Larsson DGJ. (2016) Time to limit antibiotic pollution. The medicine maker, April issue, pp 17-18. (opinion paper).
Bengtsson-Palme J, Larsson DGJ (2016). Why limit antibiotic pollution? The role of environmental selection in antibiotic resistance development. APUA Newsletter, 34(2), 6-9.
Bengtsson-Palme J, Hammarén R, Pal C, Östman M, Björlenius B, Flach C-F, Fick J, Kristiansson E, Tysklind M, Larsson DGJ. (2016). Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics. Science of the Total Environment. 572:697. https://doi.org/10.1016/j.scitotenv.2016.06.228
De Roda Husman A-M, Larsson DGJ. (2016). Risk assessment and risk management of antimicrobial resistance in the environment. AMR control 2016. Pages 104-107. Global Health Dynamics, UK.
Edman-Wallér J, Ljungström L, Jacobsson G, Andersson R, Werner M. (2016). Systemic symptoms predict presence or development of severe sepsis and septic shock. Infect Dis (Lond). 48(3):209-14. https://doi.org/10.3109/23744235.2015.1104719.
Gao C, Uzelac I, Gottfries J, Eriksson LA (2016). Exploration of multiple Sortase A protein conformations in virtual screening. Sci Rep. 5;6:20413. https://doi.org/10.1038/srep20413
Johnning A, Jakobsson H, Boulund F, Salvà Serra F, Moore ERB, Åhrén C, Karami N, Kristiansson E. (2016). Draft genome sequence of extended-spectrum β-lactamase-producing Escherichia coli, strain CCUG 62462, isolated from a urine sample" Genome Announc. 4(6):e01382-16. https://doi.org/10.1128/genomeA.01382-16
Jonsson V, Österlund T, Nerman O, Kristiansson E. (2016). Statistical evaluation of methods for identification of differentially abundant genes in comparative metagenomics. BMC Genom. 17:78. https://doi.org/10.1186/s12864-016-2386-y
Jonsson V, Österlund T, Nerman O, Kristiansson E. (2016). Variability in metagenomic count data and its influence on the identification of differentially abundant genes. J Comput Biol. 24(4):311-326. https://doi.org/10.1089/cmb.2016.0180
Karami N, Wold AE, Adlerberth I. (2016). Antibiotic resistance is linked to carriage of papC and iutA virulence genes and phylogenetic group D background in commensal and uropathogenic Escherichia coli from infants and young children. Eur J Clin Microbiol Infect Dis. 36(4): 721–729. https://doi.org/10.1007/s10096-016-2854-y
Kwiecinski J, Peetermans M, Liesenborghs L, Na M, Björnsdottir H, Zhu X, Jacobsson G, Johansson BR, Geoghegan JA, Foster TJ, Josefsson E, Bylund J, Verhamme P, Jin T. (2016). Staphylokinase control of Staphylococcus aureus biofilm formation and detachment through host plasminogen activation. J Infect Dis. 213(1):139-48. https://doi.org/10.1093/infdis/jiv360
Larsson DGJ, Svennerholm A-M (2016). The role of antibacterial agents in the development of antibiotic resistance (in Swedish). Läkartidningen 2016;113:D44E.
Marathe NP, Shetty SA, Shouche YS, Larsson DGJ. (2016). Limited bacterial diversity within a treatment plant receiving antibiotic-containing waste from bulk drug production. PloS One 11(11): e0165914. https://doi.org/10.1371/journal.pone.0165914
Munthe C. Antibiotikaresistens och etik. Ord & Bild, (5)64-68, 2016.
Müller V, Karami N, Nyberg LK, Pichler C, Torche Pedreschi PC, Quaderi S, Fritzsche J, Ambjörnsson T, Åhrén C, Westerlund F. (2016). Rapid tracing of resistance plasmids in a nosocomial outbreak using optical DNA mapping. ACS Infect Dis. 2(5):322-8. https://doi.org/10.1021/acsinfecdis.6b00017
Müller V, Rajer F, Frykholm K, Nyberg LK, Quaderi S, Fritzsche J, Kristiansson E, Ambjörnsson T, Sandegren L, Westerlund F. (2016). Direct identification of antibiotic resistance genes on single plasmid molecules using CRISPR/Cas9 in combination with optical DNA mapping. Sci Rep. 6:37938. https://doi.org/10.1038/srep37938
Nyberg LK, Quaderi S, Emilsson G, Karami N, Lagerstedt E, Müller V, Noble C, Hammarberg S, Nilsson AN, Sjöberg F, Fritzsche J, Kristiansson E, Sandegren L, Ambjörnsson T, Westerlund F. (2016). Rapid identification of intact bacterial resistance plasmids via optical mapping of single DNA molecules. Sci Rep. 6:30410. https://doi.org/10.1038/srep30410
Pal C, Bengtsson-Palme J, Kristiansson E, Larsson DGJ. (2016). The structure and diversity of human, animal and environmental resistomes. Microbiome. 4:54. https://doi.org/10.1186/s40168-016-0199-5.
Pereira MB, Kristiansson E, Axelsson-Fisk M. (2016). HattCI: fast and accurate attC site identification using hidden Markov models. J Comput Biol, 23(11):891-902. https://doi.org/10.1089/cmb.2016.0024
Runesson J, Shamansurova E, Jacobsson G. (2016). Antibiotics are being misused to treat diarrhoeal disease in children in Central Asia. Acta Paediatr. 105(12):1382-1383. https://doi.org/10.1111/apa.13583
Rönnerstrand B. Antibiotikaresistens och det kollektiva handlandets problem. Ord & Bild, (5)56-63, 2016.
Rönnerstrand B, Jagers S, Larsson DGJ. (2016). Who worries about antibiotic resistance? (In Swedish). Ekvilibrium (Eds. Oscarsson H, Ohlsson J, Solevid M). SOM-institutet, University of Gothenburg. ISBN 978-91-89673-35-9.
Salvà-Serra F, Jakobsson HE, Thorell K, Gonzales-Siles L, Hallbäck ET, Jaén-Luchoro D, Boulund F, Sikora P, Karlsson R, Svensson L, Bennasar A, Engstrand L, Kristiansson E, Moore ER. (2016). Draft genome sequence of Streptococcus gordonii type strain CCUG 33482T. Genome Announc. 4(2): e00175-16. https://doi.org/10.1128/genomeA.00175-16
Skyman E, Lindahl B, Bergbom I, Sjöström HT, Åhrén C. (2016). Being Met as marked - patients' experiences of being infected with community-acquired methicillin-resistant Staphylococcus aureus (MRSA). Scand J Caring Sci. 30(4):813-820. https://doi.org/10.1111/scs.12309
Swerkersson S, Jodal U, Åhrén C, Sixt R, Stokland E, Hansson S. (2016). Urinary tract infection in infants: the significance of low bacterial count. Pediatr Nephrol. 31(2):239-45. https://doi.org/10.1007/s00467-015-3199-y
Svensson J, Verdinelli C. (2016). Mirakellösningen som blev ett problem. Ord & Bild, (5)36-41.
Wehrli PM, Angerer TB, Farewell A, Fletcher JS, Gottfries J. (2016). Investigating the role of the stringent response in lipid modifications during the stationary phase in E. coli by direct analysis with time-of-flight-secondary ion mass spectrometry. Anal Chem. 88(17):8680-8. https://doi.org/10.1021/acs.analchem.6b01981
Bengtsson-Palme J, Boulund F, Edström R, Feizi A, Johnning A, Jonsson VA, Karlsson FH, Pal C, Pereira MB, Rehammar A, Sanchez J, Sanli K, Thorell K. (2016). Strategies to improve usability and preserve accuracy in biological sequence databases. Proteomics. 16(18):2454-60. https://doi.org/10.1002/pmic.201600034
Zaborowska M, Tillander J, Branemark R, Hagberg L, Thomsen P, Trobos M. (2016). Biofilm formation and antimicrobial susceptibility of staphylococci and enterococci from osteomyelitis associated with percutaneous orthopaedic implants. J Biomed Mater Res B Appl Biomater. 105(8):2630-2640. https://doi.org/10.1002/jbm.b.33803

Last modified

17 March 2023